Santa Cruz Vacations & Trips from $384

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Top destinations in Santa Cruz

A tortoise in a lush green forest.

Santa Rosa

Santa Rosa
A coastal landscape with clear turquoise waters, a sandy beach, and volcanic rocks.

Puerto Ayora

Puerto Ayora

The Latest Santa Cruz Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Casa de Nelly

Casa de Nelly

$384
per person
Nov 23 - Nov 26
found 11 hours ago
Roundtrip flight included
Guayaquil (GYE) to San Cristobal (SCY)
8.6/10 Excellent! (9 reviews)
Great spot, close to everything, staff was very helpful, beautiful view from up top

Reviewed on Apr 16, 2026

BAY VIEW HOUSE

BAY VIEW HOUSE

$472
per person
Nov 23 - Nov 26
found 1 day ago
Roundtrip flight included
Guayaquil (GYE) to Isla Baltra (GPS)
9.6/10 Exceptional! (9 reviews)
Bay View Inn was right in the heart of town, yet the apartment felt peaceful and quiet. Spacious and well-kept, with a friendly, helpful host. Would definitely recommend!

Reviewed on Aug 11, 2026

Galapagos Planet Hotel

Galapagos Planet Hotel

$452
per person
Nov 23 - Nov 26
found 1 day ago
Roundtrip flight included
Guayaquil (GYE) to San Cristobal (SCY)
8/10 Very Good! (45 reviews)
Hotel Albemarle Galapagos Beachfront

Hotel Albemarle Galapagos Beachfront

$1,226
per person
Oct 27 - Nov 2
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Isla Baltra (GPS)
9/10 Wonderful! (110 reviews)
This is a very nice hotel with good location and very helpful staff

Reviewed on Sep 8, 2026

Finch Bay Galapagos Hotel

Finch Bay Galapagos Hotel

$2,292
per person
Nov 29 - Dec 4
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Isla Baltra (GPS)
9.4/10 Exceptional! (104 reviews)

Find the Best Santa Cruz Vacation Packages

Santa Cruz Essential Information

Language
Spanish
Currency
U.S dollars
Local Welcome
¡Hola!
Local Goodbye
Adiós

Santa Cruz Hotel Deals

Hotel Fiesta

Hotel Fiesta

Calle Moises Brito y Juan Montalvo Puerto Ayora Galapagos
Fully refundableReserve now, pay when you stay
$117 nightly
$117 total
Oct 17 - Oct 18
9/10 Wonderful! (437 reviews)
"Room was clean but basic. Nice pool and breakfast"

Reviewed on Sep 15, 2026

Hotel Fiesta
Finch Bay Galapagos Hotel

Finch Bay Galapagos Hotel

Barrio Punta Estrada Puerto Ayora Galapagos
$552 nightly
$607 total
Sep 30 - Oct 1
Finch Bay Galapagos Hotel
Maidith Galapagos Inn

Maidith Galapagos Inn

Calle Cucuve #341 y Seymour, Santa Cruz Puerto Ayora Galápagos
$104 nightly
$104 total
Sep 24 - Sep 25
10/10 Exceptional! (162 reviews)
"Staff are super helpful and friendly, location is good, breakfast is varied and tasty, beds are comfortable. Only downside is the lights are bright white in the rooms."

Reviewed on Sep 15, 2026

Maidith Galapagos Inn
See all 221 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Santa Cruz attractions

A beach with a small island in the distance.
Photo by Elizabeth Oates

Tortuga Bay Beach

9.6/10 (488 reviews)
If a restful vacation is part of your travel plans, Tortuga Bay Beach might be the perfect place to seek out during your trip to Bella Vista. While you're in the area, wander around the parks.
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A rocky shoreline with mangrove trees and calm ocean waters.
Photo by Luis Felipe

El Garrapatero Beach

9.2/10 (154 reviews)
Why not spend a carefree afternoon at El Garrapatero Beach during your travels in El Cascajo? While you're in the area, wander around the parks.
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Playa de los Alemanes

8.8/10 (262 reviews)
If a restful vacation is part of your travel plans, Playa de los Alemanes might be the perfect place to seek out during your trip to Puerto Ayora. While you're here, you can savor the top-notch restaurants.
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Malecon

9.2/10 (350 reviews)
You can find out about the history of Puerto Ayora with a visit to Malecon. Wander the waterfront and beaches in the area.
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Los Gemelos Sinkholes

9.2/10 (143 reviews)
Commune with nature and explore the great outdoors at Los Gemelos Sinkholes during your travels in Santa Rosa. Wander the waterfront and beaches in the area.
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What to do in Santa Cruz

El Chato 2 Reserve Admission Ticket in Santa Cruz Island

El Chato 2 Reserve Admission Ticket in Santa Cruz Island

$8
per traveler
El Chato 2 Reserve Admission Ticket in Santa Cruz Island
Private Tour Sighting Giant Tortoises and Lava Tunnels

Giant Turtle Watching and Lava Tunnels Tour

$40
per adult
Giant Turtle Watching and Lava Tunnels Tour
Half Day Bay Tour in Santa Cruz Island

Half Day Bay Tour in Santa Cruz Island

$80
per adult
Half Day Bay Tour in Santa Cruz Island
See all activities in Santa Cruz
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