Santa Cruz Vacations & Trips from $789
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to $2,000 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Top destinations in Santa Cruz
Puerto Ayora
Santa Rosa
The Latest Santa Cruz Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Hotel Albemarle Galapagos Beachfront
Price was $1,302, price is now $906 per person
$906
per person
Aug 6 - Aug 10
found 13 hours ago
Roundtrip flight included
Cuenca (CUE) to Isla Baltra (GPS)
9/10 Wonderful! (105 reviews)
Great location right on the beach and just a 10 minute walk to the pier.
Reviewed on Apr 23, 2026
Angermeyer Waterfront Inn
Price was $1,388, price is now $1,007 per person
$1,007
per person
Aug 6 - Aug 10
found 13 hours ago
Roundtrip flight included
Cuenca (CUE) to Isla Baltra (GPS)
9.4/10 Exceptional! (133 reviews)
Beautiful hotel, with friendly welcoming staff, awesome choice of meals, definitely recommend it! Easy to get to the town, a beach closeby and spacious rooms facing the waters....plenty of wildlife around
Reviewed on May 14, 2026
Royal Palm Galapagos, Curio Collection Hotel by Hilton
Price was $2,073, price is now $1,567 per person
$1,567
per person
Aug 6 - Aug 10
found 13 hours ago
Roundtrip flight included
Cuenca (CUE) to Isla Baltra (GPS)
9.4/10 Exceptional! (57 reviews)
Arrived late and left early the next day to catch a flight so did not have the luxury of spending as much time at the resort as we would have liked. Spacious comfy rooms and excellent staff and food!
Reviewed on Mar 30, 2026
Find the Best Santa Cruz Vacation Packages
Santa Cruz Essential Information
Language | Spanish |
|---|---|
Currency | U.S dollars |
Local Welcome | ¡Hola! |
Local Goodbye | Adiós |
Santa Cruz Hotel Deals
Hotel Fiesta
Calle Moises Brito y Juan Montalvo Puerto Ayora Galapagos
Fully refundableReserve now, pay when you stay
$152 nightly
The price is $152 total per night from May 18 to May 19
$152 total
May 18 - May 19
9/10 Wonderful! (407 reviews)
Clean, good location
Reviewed on May 7, 2026
Finch Bay Galapagos Hotel
Barrio Punta Estrada Puerto Ayora Galapagos
$561 nightly
The price is $618 total per night from Jun 8 to Jun 9
$618 total
Jun 8 - Jun 9
9.4/10 Exceptional! (99 reviews)
Highly recomended
Reviewed on May 1, 2026
Maidith Galapagos Inn
Calle Cucuve #341 y Seymour, Santa Cruz Puerto Ayora Galápagos
$120 nightly
The price is $120 total per night from May 18 to May 19
$120 total
May 18 - May 19
10/10 Exceptional! (133 reviews)
Very good staff! Nico was great thank you!
Reviewed on May 8, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Explore a world of travel with Expedia
Other vacations you might like
- January Vacations and Deals
- February Vacations and Deals
- March Vacations and Deals
- April Vacations and Deals
- May Vacations and Deals
- June Vacations and Deals
- July Vacations and Deals
- August Vacations and Deals
- September Vacations and Deals
- October Vacations and Deals
- November Vacations and Deals
- December Vacations and Deals
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
